ABSTRACT This article focuses on the phylogeny of the human hand. Paralleling his earlier work on the evolution of bipedalism from Ardipithecus through Australopithecus to the genus Homo, Boblett examines the no-less-radical development of the hand. Though our hands look far more similar to those of our simian ancestors than is the case with our feet, the changes in structure and function are no less profound. Boblett concludes with some practical advice on self-care of hands for Rolfers.